High relapse-free survival after preoperative and intraoperative radiotherapy and resection for sulcus superior tumors.
نویسندگان
چکیده
STUDY OBJECTIVES Relapse-free survival in patients with sulcus superior tumors. DESIGN Prospective registration study. SETTING Department of surgical oncology of a university hospital. PATIENTS Twenty-one patients treated with preoperative radiotherapy (46 Gy), lobectomy and chest-wall resection, and intraoperative radiotherapy (10 Gy). RESULTS After a median follow-up of 18 months, 18 patients (85%) were free from locoregional relapse, while 8 patients were still alive. CONCLUSIONS The results show that this protocol can achieve excellent local tumor control and can even be used for palliative treatment.
منابع مشابه
Trimodality therapy for superior sulcus non-small cell lung cancer: Southwest Oncology Group-Intergroup Trial S0220.
BACKGROUND Although preoperative chemotherapy (cisplatin-etoposide) and radiotherapy, followed by surgical resection, is considered a standard of care for superior sulcus cancers, treatment is rigorous and relapse limits long-term survival. The Southwest Oncology Group-Intergroup Trial S0220 was designed to incorporate an active systemic agent, docetaxel, as consolidation therapy. METHODS Pat...
متن کاملAnterior Trans Cervicothoracic Approach for Complete Resection of Cervicothoracic Mediastinal Neurogenic Tumors
Introduction:Neurogenic mediastinal tumors comprise a wide range of benign and malignant diseases. A group of these tumors, located at thoracic apex, sometimes spread to cervical spaces causing numerous surgical difficulties. In thoracotomy approaches, due to proximity of the tumors to major blood vessels, complete removal of these tumors from cervical spaces is impossible or may cause intraope...
متن کاملPancoast Tumors: Surgical Approaches and Techniques
1.1 History Tumors of the superior sulcus represent less than 5% of lung malignancies. The distinctive symptomatology was first described by Edwin Hare in 1838 [1], and it has been nearly 80 years since clinical and radiographic features of this tumor were described by Dr Henry Pancoast, a radiologist, in 1924 [2]. As a radiologist, he noted the difficulty in detecting the tumor on a plain ches...
متن کاملReport Asco 2000 New Orleans : Lung Cancer
Non-small cell lung cancer Locally advanced stages Interesting results of a prospective SWOG trial on the multimodality treatment of sulcus superior tumors were presented (1). In many centers, sulcus superior tumors (T3 N0-1) and Pancoast tumors (T4 N0-1) are treated by preoperative low-dose radiotherapy (e.g. 30 Gy) followed by either attempted surgical resection or more radiotherapy. When com...
متن کاملSurgical treatment of superior sulcus tumors: results and prognostic factors.
OBJECTIVES To study the clinical characteristics, treatment modalities, and outcome of patients with superior sulcus tumors who underwent surgery over a 15-year period. DESIGN Retrospective clinical study. METHODS Clinical records of all patients operated on for superior sulcus tumors by the same surgical team between 1988 and 2002 were reviewed retrospectively. RESULTS Sixty-seven patien...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chest
دوره 124 5 شماره
صفحات -
تاریخ انتشار 2003